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RB1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

140.00 € - 399.00 €

Specifications

Antigen RB1
Concentration 1 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16886193
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Proteintech
10048-2-IG-20UL
20 μL
140.00 €
20µL
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16876193
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Proteintech
10048-2-IG-150UL
150 μL
399.00 €
150µL
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Description

Description

This antibody is a rabbit polyclonal antibody raised against human RB1 fusion protein.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia. Phosphorylation of Rb at S608 depends on CDK4.
Specifications

Specifications

RB1
Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation
Unconjugated
Rabbit
Human, Mouse
P06400, P13405
19645, 5925
RB1 Fusion Protein Ag0006
Primary
-20°C
RB1
1 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
OSRC, p105 Rb, pp110, pRb, RB, RB1, retinoblastoma 1
RB1
IgG
Protein A
Antibody
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