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RB1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10048-2-IG-150UL
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Description
This antibody is a rabbit polyclonal antibody raised against human RB1 fusion protein.
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia. Phosphorylation of Rb at S608 depends on CDK4.Specifications
| RB1 | |
| Polyclonal | |
| Unconjugated | |
| RB1 | |
| OSRC, p105 Rb, pp110, pRb, RB, RB1, retinoblastoma 1 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 19645, 5925 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P06400, P13405 | |
| RB1 | |
| RB1 Fusion Protein Ag0006 | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |