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Osteopontin Rabbit anti-Human, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00 € - 410.00 €
Specifications
| Antigen | Osteopontin |
|---|---|
| Concentration | 0.36 mg/mL |
| Applications | Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16842145
|
Proteintech
22952-1-AP-20UL |
20 μL |
145.00 €
20µL |
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|
16832145
|
Proteintech
22952-1-AP-150UL |
150 μL |
410.00 €
150µL |
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Description
Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in maligt glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.Specifications
| Osteopontin | |
| Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry, Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human, Rat | |
| P08721, P10451 | |
| 25353, 6696 | |
| Osteopontin Fusion Protein Ag19216 | |
| Primary | |
| -20°C | |
| SPP1 |
| 0.36 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| BNSP, Bone sialoprotein 1, BSPI, ETA 1, Nephropontin, OPN, Osteopontin, secreted phosphoprotein 1, SPP 1, SPP1, Urinary stone protein, Uropontin | |
| SPP1 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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