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Thermo Scientific Chemicals Hydrocortisone, 98%

Hydrocortisone, CAS # 50-23-7, is the pharmaceutical formulation of the hormone, cortisol, and is commonly administered as an immunosuppressive drug.

35.40 € - 1495.00 €

Chemical Identifiers

CAS 50-23-7
Molecular Formula C21H30O5
Molecular Weight (g/mol) 362.47
MDL Number MFCD00011654
InChI Key JYGXADMDTFJGBT-VWUMJDOOSA-N
Synonym hydrocortisone, cortisol, acticort, cetacort, cortef, 17-hydroxycorticosterone, hydrocortisyl, hydrasson, cobadex, cortril
PubChem CID 5754
ChEBI CHEBI:17650
IUPAC Name (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
SMILES CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Hydrocortisone is the synthetic formulation of the naturally occurring hormone, cortisol
• It is available as a white crystalline powder soluble in water, DMSO, and ethanol
• It is stable at room temperature but sensitive to light, and reactive in the presence of strong oxidizing agents

Applications

• Hydrocortisone works as an agonist to glucocorticoid receptors, thereby suppressing the inflammatory response of the immune system
• It’s administration induces gluconeogenesis, thus increasing endogenous blood sugar levels
• Research indicates a role for hydrocortisone in the metabolism of fat, protein, and carbohydrates

Specifications

Chemical Identifiers

50-23-7
362.47
JYGXADMDTFJGBT-VWUMJDOOSA-N
5754
(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
C21H30O5
MFCD00011654
hydrocortisone, cortisol, acticort, cetacort, cortef, 17-hydroxycorticosterone, hydrocortisyl, hydrasson, cobadex, cortril
CHEBI:17650
CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O

Specifications

50-23-7
White
97.5% min. (HPLC)
MFCD00011654
+150° (156°C c=1,dioxane)
hydrocortisone, cortisol, acticort, cetacort, cortef, 17-hydroxycorticosterone, hydrocortisyl, hydrasson, cobadex, cortril
JYGXADMDTFJGBT-VWUMJDOOSA-N
(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
5754
362.47
Powder
212°C to 217°C
Authentic
C21H30O5
15, 4824
+ 150
Solubility in water: 0.28g/L (25°C). Other solubilities: soluble in sulfuric acid,partially soluble in alcohol and propylene glycol,soluble in dioxane; sol (g/l) (25°C): chcl3 1.6;,ether 0.35; etoh 15; meoh 6.2; acetone 9.3;,propylene glycol 1
CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
362.47
CHEBI:17650
98%
Hydrocortisone
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Safety and Handling

Safety and Handling

GHS H Statement
May damage the unborn child.
Suspected of damaging fertility.

GHS P Statement
Obtain special instructions before use.

GHS Signal Word: Danger

missing translation for 'einecsNumber' : 200-020-1

Product Identifier
  • Hydrocortisone

Signal Word
  • Warning

Hazard Category
  • Reproductive toxicity Category 2

Hazard Statement
  • H361f-Suspected of damaging fertility.

Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only