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  6. Thermo Scientific Chemicals Hydrocortisone, 98%

Thermo Scientific Chemicals Hydrocortisone, 98%

Product Code. 10062031
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Quantity:
1 g
5 g
25 g
100 g
Packaging:
Glass bottle

Description

Hydrocortisone, CAS # 50-23-7, is the pharmaceutical formulation of the hormone, cortisol, and is commonly administered as an immunosuppressive drug.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Hydrocortisone is the synthetic formulation of the naturally occurring hormone, cortisol
• It is available as a white crystalline powder soluble in water, DMSO, and ethanol
• It is stable at room temperature but sensitive to light, and reactive in the presence of strong oxidizing agents

Applications

• Hydrocortisone works as an agonist to glucocorticoid receptors, thereby suppressing the inflammatory response of the immune system
• It’s administration induces gluconeogenesis, thus increasing endogenous blood sugar levels
• Research indicates a role for hydrocortisone in the metabolism of fat, protein, and carbohydrates

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 50-23-7
Molecular Formula C21H30O5
Molecular Weight (g/mol) 362.47
MDL Number MFCD00011654
InChI Key JYGXADMDTFJGBT-VWUMJDOOSA-N
Synonym hydrocortisone, cortisol, acticort, cetacort, cortef, 17-hydroxycorticosterone, hydrocortisyl, hydrasson, cobadex, cortril
PubChem CID 5754
ChEBI CHEBI:17650
IUPAC Name (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
SMILES CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O

Specifications

Melting Point 212°C to 217°C
Color White
Infrared Spectrum Authentic
Assay Percent Range 97.5% min. (HPLC)
Packaging Glass bottle
Quantity 1 g
Merck Index 15, 4824
Specific Rotation Condition +150° (156°C c=1,dioxane)
Specific Rotation + 150
Solubility Information Solubility in water: 0.28g/L (25°C). Other solubilities: soluble in sulfuric acid,partially soluble in alcohol and propylene glycol,soluble in dioxane; sol (g/l) (25°C): chcl3 1.6;,ether 0.35; etoh 15; meoh 6.2; acetone 9.3;,propylene glycol 1
Formula Weight 362.47
Percent Purity 98%
Physical Form Powder
Chemical Name or Material Hydrocortisone
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Safety and Handling

compliance-icons
Product Identifier
  • Hydrocortisone
 Signal Word
  • Warning
 Hazard Category
  • Reproductive toxicity Category 2
 Hazard Statement
  • H361f-Suspected of damaging fertility.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.

RUO – Research Use Only

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