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CYR61/CCN1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 € - 410.00 €

Specifications

Antigen CYR61/CCN1
Concentration 0.33 mg/mL
Applications Immunofluorescence, Western Blot, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16865085
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Proteintech
26689-1-AP-20UL
20 μL
145.00 €
20µL
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16855085
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Proteintech
26689-1-AP-150UL
150 μL
410.00 €
150µL
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Description

Description

CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
Specifications

Specifications

CYR61/CCN1
Immunofluorescence, Western Blot, Immunocytochemistry
Unconjugated
Rabbit
Human
O00622
3491
CYR61/CCN1 Fusion Protein Ag25129
Primary
-20°C
CYR61
0.33 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CCN family member 1, CCN1, CYR61, GIG1, IBP 10, IGF binding protein 10, IGFBP 10, IGFBP10, Protein CYR61, Protein GIG1
CYR61
IgG
Antigen Affinity Chromatography
Antibody
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Documents

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