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CYR61/CCN1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 26689-1-AP-150UL
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Description
CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.Specifications
| CYR61/CCN1 | |
| Polyclonal | |
| Unconjugated | |
| CYR61 | |
| CCN family member 1, CCN1, CYR61, GIG1, IBP 10, IGF binding protein 10, IGFBP 10, IGFBP10, Protein CYR61, Protein GIG1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3491 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Western Blot | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O00622 | |
| CYR61 | |
| CYR61/CCN1 Fusion Protein Ag25129 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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