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Cdc20 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 € - 410.00 €

Specifications

Antigen Cdc20
Concentration 0.33 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16816523
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Proteintech
10252-1-AP-20UL
20 μL
145.00 €
20µL
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16806523
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Proteintech
10252-1-AP-150UL
150 μL
410.00 €
150µL
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Description

Description

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
Specifications

Specifications

Cdc20
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
Rabbit
Human
Q12834
991
Cdc20 Fusion Protein Ag0295
Primary
-20°C
CDC20
0.33 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CDC20, CDC20A, p55CDC
CDC20
IgG
Antigen Affinity Chromatography
Antibody
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