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Cdc20 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10252-1-AP-150UL
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Description
Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.Specifications
| Cdc20 | |
| Polyclonal | |
| Unconjugated | |
| CDC20 | |
| CDC20, CDC20A, p55CDC | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 991 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q12834 | |
| CDC20 | |
| Cdc20 Fusion Protein Ag0295 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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