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1-Methylpiperazine, 98+%, Thermo Scientific Chemicals
37.08 € - 477.38 €
Chemical Identifiers
| CAS | 109-01-3 |
|---|---|
| Molecular Formula | C5H12N2 |
| Molecular Weight (g/mol) | 100.165 |
| MDL Number | MFCD00005966 |
| InChI Key | PVOAHINGSUIXLS-UHFFFAOYSA-N |
| Synonym | n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine |
| PubChem CID | 53167 |
| IUPAC Name | 1-methylpiperazine |
| SMILES | CN1CCNCC1 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
11429802
|
Thermo Scientific Alfa Aesar
A10837.AE |
100 mL |
37.08 €
100mL |
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|
11439802
|
Thermo Scientific Alfa Aesar
A10837.AP |
500 mL |
119.60 €
500mL |
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|
11449802
|
Thermo Scientific Alfa Aesar
A10837.0F |
2500 mL |
477.38 €
2500mL |
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Description
1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.
Solubility
Miscible with water and methanol.
Notes
Hygroscopic. Moisture sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.
Chemical Identifiers
| 109-01-3 | |
| 100.165 | |
| PVOAHINGSUIXLS-UHFFFAOYSA-N | |
| 53167 | |
| CN1CCNCC1 |
| C5H12N2 | |
| MFCD00005966 | |
| n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine | |
| 1-methylpiperazine |
Specifications
| 109-01-3 | |
| 0.903 | |
| 34°C (93°F) | |
| C5H12N2 | |
| MFCD00005966 | |
| 102724 | |
| n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine | |
| PVOAHINGSUIXLS-UHFFFAOYSA-N | |
| 1-methylpiperazine | |
| 53167 | |
| ≥98% |
| -6°C | |
| 137°C to 139°C | |
| Amine-like | |
| 1.4655 | |
| UN2734 | |
| Air Sensitive | |
| Miscible with water and methanol. | |
| CN1CCNCC1 | |
| 100.165 | |
| 100.17 | |
| 1-Methylpiperazine |
Safety and Handling
GHS H Statement
H331-H314-H318-H226-H302-H312
Toxic if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
Harmful if swallowed.
Harmful in contact with skin.
P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c
H226-H302+H312+H332-H314-H317-H335
missing translation for 'dotInformation' : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: AMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S.
missing translation for 'einecsNumber' : 203-639-5
missing translation for 'rtecsNumber' : TM1225000
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures; Store under Argon
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- 1-Methylpiperazine
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 1
- Flammable liquid Category 3
- Skin corrosion/irritation Category 1 B
Hazard Statement
- H226-Flammable liquid and vapour.
- H312-Harmful in contact with skin.
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H332-Harmful if inhaled.
Precautionary Statement
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
Supplemental information
- MIXTURE LIST-Contains : 1-Methylpiperazine
RUO – Research Use Only
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