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ZNRF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 € - 410.00 €

Specifications

Antigen ZNRF2
Concentration 0.25 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16879714
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Proteintech
20200-1-AP-20UL
20 μL
145.00 €
20µL
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16869714
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Proteintech
20200-1-AP-150UL
150 μL
410.00 €
150µL
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Description

Description

The antibody is specific to ZNRF2.

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF2 (zinc and ring finger 2), also known as RNF202, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, as well as the endosome and the cell junction. Expressed at high levels in brain tissue, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintece of neuronal transmission and plasticity. Upon DNA damage, ZNRF2 is subject to phosphorylation, probably by ATR or ATM.
Specifications

Specifications

ZNRF2
Western Blot
Unconjugated
Rabbit
Mouse, Human, Rat
Q71FD5, Q8NHG8
223082, 362367, 387524
Peptide
Primary
-20°C
ZNRF2
0.25 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Protein Ells2, RING finger protein 202, RNF202, zinc and ring finger 2, Zinc/RING finger protein 2, ZNRF2
Znrf2
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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