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UNC13A/Munc13-1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 55053-1-AP-150UL
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Description
The antibody is specific to UNC13A.
UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion.Specifications
| UNC13A/Munc13-1 | |
| Polyclonal | |
| Unconjugated | |
| UNC13A | |
| KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A (C. elegans), UNC13A | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 23025, 382018 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 0.33 mg/mL | |
| 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q4KUS2, Q9UPW8 | |
| Unc13a | |
| Peptide | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |