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TUSC2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11538-1-AP-20UL

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Product Code. 16858683

  • 132.87 € / 20µL

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Description

Description

TUSC2 (tumor suppressor candidate 2), also known as FUS1, LGCC or PDAP2, is a 110 amino acid protein that is expressed at high levels in kidney, pancreas, lung, heart and skeletal muscle where it is thought to function as a tumor suppressor. More specifically, TUSC2 inhibits invasive colony formation by inducing G1 cell cycle arrest and ultimately causing apoptosis, thereby preventing tumor growth. The gene encoding TUSC2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
Specifications

Specifications

TUSC2
Polyclonal
Unconjugated
TUSC2
C3orf11, Fus 1 protein, FUS1, Fusion 1 protein, LGCC, PAP, PDAP2, PDGFA associated protein 2, tumor suppressor candidate 2, TUSC2
Rabbit
Antigen Affinity Chromatography
RUO
11334, 501052, 80385
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O75896, Q9WVF8
Tusc2
TUSC2 Fusion Protein Ag2118
20 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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