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  7. Thermo Scientific Chemicals Trimethoprim, 98%

Thermo Scientific Chemicals Trimethoprim, 98%

Product Code. 15790889
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Quantity:
5 g
25 g
100 g
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Description

Trimethoprim, CAS # 738-70-5, is a trimethoxybenzyl-pyrimidine used as an antimicrobial.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Trimethoprim is a synthetic pyrimidine analog that binds dihydrofolate-reductase and inhibits the synthesis of folic acid; when paired with sulfamethoxazole, its activity is enhanced • Trimethoprim has antibacterial and antiprotozoal properties

Applications

• Trimethoprim inhibits the conversion of para-aminobenzoic acid (PABA) to folic acid near the end of the synthesis pathway and can be used to study related effects

• Trimethoprim has been radiolabeled and used to trace routes of infection, and it also has been used experimentally as a fluorescent labeler to quantify dihydrofolate-reductase expression

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 738-70-5
Molecular Formula C14H18N4O3
Molecular Weight (g/mol) 290.32
InChI Key IEDVJHCEMCRBQM-UHFFFAOYSA-N
Synonym trimethoprim, proloprim, trimpex, bactramin, monotrim, monotrimin, trimetoprim, trimopan, monoprim, syraprim
PubChem CID 5578
ChEBI CHEBI:45924
IUPAC Name 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
SMILES COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N

Specifications

Melting Point 234.0°C to 236.0°C
Loss on Drying 0.5% max. (105°C, 4 h)
Infrared Spectrum Authentic
Assay Percent Range 97.5% min. (HPLC)
Quantity 100 g
Solubility Information Solubility in water: insoluble.
Formula Weight 290.32
Percent Purity 98%
Chemical Name or Material Trimethoprim

Safety and Handling

compliance-icons
Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
 Hazard Statement
  • H302-Harmful if swallowed.
 Precautionary Statement
  • P264-Wash thoroughly after handling.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.

RUO – Research Use Only

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