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  7. Trifluoroacetic acid, HPLC Grade, 99.5+%, Thermo Scientific Chemicals

Trifluoroacetic acid, HPLC Grade, 99.5+%, Thermo Scientific Chemicals

Product Code. 11465440
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Quantity:
100 mL
500 mL
4 x 100 mL
4 x 500 mL
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and ceramic compounds. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. It finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 76-05-1
Molecular Formula C2HF3O2
Molecular Weight (g/mol) 114.02
MDL Number MFCD00004169
InChI Key DTQVDTLACAAQTR-UHFFFAOYSA-N
Synonym trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
PubChem CID 6422
ChEBI CHEBI:45892
IUPAC Name 2,2,2-trifluoroacetic acid
SMILES OC(=O)C(F)(F)F

Specifications

Melting Point -15°C
Boiling Point 72°C to 73°C
Color Colorless
Assay Percent Range >99.5%
UN Number 2699
Beilstein 742035
Solubility Information Miscible with water,ether,acetone,ethanol,benzene,hexane and carbon tetrachloride.
Formula Weight 114.02
Grade HPLC
Density 1.48 g/cm3 at 20°C
Quantity 100 mL
Odor Pungent
Physical Form Liquid
Refractive Index 1.284
Sensitivity Hygroscopic
Vapor Pressure 8mm Hg at 20°C
Chemical Name or Material Trifluoroacetic Acid, Water 0.1%
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Safety and Handling

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Product Identifier
  • Trifluoroacetic acid
 Signal Word
  • Danger
 Hazard Category
  • Skin corrosion/irritation Category 1 A
  • Acute toxicity Category 4
  • LONG-TERM AQUATIC HAZARD Chronic 3
 Hazard Statement
  • H332-Harmful if inhaled.
  • H314-Causes severe skin burns and eye damage.
  • H412-Harmful to aquatic life with long lasting effects.
 Precautionary Statement
  • P260-Do not breathe dust/fume/gas/mist/vapours/spray.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P405-Store locked up.
  • P501-Dispose of contents/container to .

RUO – Research Use Only

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