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Thermo Scientific Chemicals Trifluoroacetic acid, biochemical grade, 99.5+%
47.54 € - 445.22 €
Chemical Identifiers
| CAS | 76-05-1 |
|---|---|
| Molecular Formula | C2HF3O2 |
| Molecular Weight (g/mol) | 114.02 |
| MDL Number | MFCD00004169 |
| InChI Key | DTQVDTLACAAQTR-UHFFFAOYSA-N |
| Synonym | trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova |
| PubChem CID | 6422 |
| ChEBI | CHEBI:45892 |
| IUPAC Name | trifluoroacetic acid |
| SMILES | OC(=O)C(F)(F)F |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
11436947
|
Thermo Scientific Chemicals
A14365.18 |
50 g |
47.54 €
50g |
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|
11446947
|
Thermo Scientific Chemicals
A14365.30 |
250 g |
143.72 €
250g |
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|
11426947
|
Thermo Scientific Chemicals
A14365.0B |
1000 g |
445.22 €
1000g |
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Description
Used to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsUsed to cleave peptide blocking groupsThe combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
Solubility
Miscible with ether, acetone, ethanol, benzene, hexane and carbon tetrachloride.
Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.
Chemical Identifiers
| 76-05-1 | |
| 114.02 | |
| DTQVDTLACAAQTR-UHFFFAOYSA-N | |
| 6422 | |
| trifluoroacetic acid |
| C2HF3O2 | |
| MFCD00004169 | |
| trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova | |
| CHEBI:45892 | |
| OC(=O)C(F)(F)F |
Specifications
| 76-05-1 | |
| 72°C to 73°C | |
| MFCD00004169 | |
| 742035 | |
| trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova | |
| DTQVDTLACAAQTR-UHFFFAOYSA-N | |
| trifluoroacetic acid | |
| 6422 | |
| 114.02 | |
| Biochemical | |
| Pungent | |
| Hygroscopic |
| -15°C | |
| C2HF3O2 | |
| UN2699 | |
| 14,9681 | |
| Miscible with ether,acetone,ethanol,benzene,hexane and carbon tetrachloride. | |
| OC(=O)C(F)(F)F | |
| 114.02 | |
| CHEBI:45892 | |
| ≥99.5% | |
| 1.48 | |
| 1.284 | |
| Trifluoroacetic acid |
Safety and Handling
GHS H Statement
H314-H332
Causes severe skin burns and eye damage.
Harmful if inhaled.
P234-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P390-P501c
H290-H314-H332-H335
missing translation for 'dotInformation' : Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: TRIFLUOROACETIC ACID
missing translation for 'einecsNumber' : 200-929-3
missing translation for 'rtecsNumber' : AJ9625000
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Trifluoroacetic acid
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 4
- LONG-TERM AQUATIC HAZARD Chronic 3
- Serious eye damage/eye irritation Category 1
- Skin corrosion/irritation Category 1 A
Hazard Statement
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H332-Harmful if inhaled.
- H412-Harmful to aquatic life with long lasting effects.
- EUH071-Corrosive to the respiratory tract.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
Supplemental information
- MIXTURE LIST-Contains : Trifluoroacetic acid
RUO – Research Use Only
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Product Title
Thermo Scientific Chemicals Trifluoroacetic acid, biochemical grade, 99.5+%