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Trifluoroacetic acid, 99%, Thermo Scientific Chemicals

28.94 € - 249.24 €

Chemical Identifiers

CAS 76-05-1
Molecular Formula C2HF3O2
Molecular Weight (g/mol) 114.02
MDL Number MFCD00004169
InChI Key DTQVDTLACAAQTR-UHFFFAOYSA-N
Synonym trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
PubChem CID 6422
ChEBI CHEBI:45892
IUPAC Name trifluoroacetic acid
SMILES OC(=O)C(F)(F)F
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Products 3
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Product Code Brand Quantity Price Quantity & Availability  
11372486
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Thermo Scientific Alfa Aesar
L06374.AC
25 mL
28.94 €
25mL
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11382486
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Thermo Scientific Alfa Aesar
L06374.AE
100 mL
66.33 €
100mL
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11392486
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Thermo Scientific Alfa Aesar
L06374.AP
500 mL
249.24 €
500mL
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Description

Description

The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.

Solubility
Miscible with ether, acetone, ethanol, benzene, hexane and carbon tetrachloride.

Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.
Specifications

Chemical Identifiers

76-05-1
114.02
DTQVDTLACAAQTR-UHFFFAOYSA-N
6422
trifluoroacetic acid
C2HF3O2
MFCD00004169
trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
CHEBI:45892
OC(=O)C(F)(F)F

Specifications

76-05-1
72°C to 73°C
CF3CO2H
UN2699
14,9681
Miscible with ether,acetone,ethanol,benzene,hexane and carbon tetrachloride.
OC(=O)C(F)(F)F
114.02
CHEBI:45892
99%
Pungent
Hygroscopic
-15°C
C2HF3O2
MFCD00004169
742035
trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoroacetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
DTQVDTLACAAQTR-UHFFFAOYSA-N
trifluoroacetic acid
6422
114.02
1.48
1.284
Trifluoroacetic acid
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Safety and Handling

Safety and Handling

GHS H Statement
H314-H332
Causes severe skin burns and eye damage.
Harmful if inhaled.

P234-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P390-P501c

H290-H314-H332-H335

missing translation for 'dotInformation' : Transport Hazard Class: 8; Packing Group: I; Proper Shipping Name: TRIFLUOROACETIC ACID

missing translation for 'einecsNumber' : 200-929-3

missing translation for 'rtecsNumber' : AJ9625000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier
  • Trifluoroacetic acid

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 4
  • LONG-TERM AQUATIC HAZARD Chronic 3
  • Serious eye damage/eye irritation Category 1
  • Skin corrosion/irritation Category 1 A

Hazard Statement
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • H332-Harmful if inhaled.
  • H412-Harmful to aquatic life with long lasting effects.
  • EUH071-Corrosive to the respiratory tract.

Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.

Supplemental information
  • MIXTURE LIST-Contains : Trifluoroacetic acid

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only