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TMEM41B Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 € - 410.00 €

Specifications

Antigen TMEM41B
Concentration 400 μg/mL
Applications Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
17211446
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Proteintech
29270-1-AP-20UL
20 μL
145.00 €
20µL
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17201446
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Proteintech
29270-1-AP-150UL
150 μL
410.00 €
150µL
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Description

Description

Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.

Specifications

Specifications

TMEM41B
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Unconjugated
Rabbit
440026
400 μg/mL
Polyclonal
Liquid
Human, Mouse
Primary
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