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TMEM41B Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00 € - 410.00 €
Specifications
Antigen | TMEM41B |
---|---|
Concentration | 400 μg/mL |
Applications | Western Blot, Immunohistochemistry, Immunofluorescence, ELISA |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17211446
|
Proteintech
29270-1-AP-20UL |
20 μL |
145.00 €
20µL |
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17201446
|
Proteintech
29270-1-AP-150UL |
150 μL |
410.00 €
150µL |
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Description
Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.
Specifications
TMEM41B | |
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA | |
Unconjugated | |
Rabbit | |
440026 |
400 μg/mL | |
Polyclonal | |
Liquid | |
Human, Mouse | |
Primary |