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tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals

33.10 € - 376.00 €

Chemical Identifiers

CAS 18162-48-6
Molecular Formula C6H15ClSi
Molecular Weight (g/mol) 150.721
MDL Number MFCD00000501
InChI Key BCNZYOJHNLTNEZ-UHFFFAOYSA-N
Synonym tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
PubChem CID 28928
ChEBI CHEBI:85071
IUPAC Name tert-butyl-chloro-dimethylsilane
SMILES CC(C)(C)[Si](C)(C)Cl
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Thermo Scientific Alfa Aesar
A13064.06
5 g
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Thermo Scientific Alfa Aesar
A13064.14
25 g
141.00 €
25g
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Thermo Scientific Alfa Aesar
A13064.22
100 g
376.00 €
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Description

Description

tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.

Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.

Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
Specifications

Chemical Identifiers

18162-48-6
150.721
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
28928
tert-butyl-chloro-dimethylsilane
C6H15ClSi
MFCD00000501
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
CHEBI:85071
CC(C)(C)[Si](C)(C)Cl

Specifications

124°C to 126°C
18162-48-6
(CH3)3CSi(CH3)2Cl
UN2925
22°C (72°F)
Soluble in chloroform and ethyl acetate. Insoluble in water.
CC(C)(C)[Si](C)(C)Cl
150.721
CHEBI:85071
97%
Moisture sensitive
tert-Butyldimethylchlorosilane
86°C to 89°C
C6H15ClSi
MFCD00000501
505999
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
tert-butyl-chloro-dimethylsilane
28928
150.73
Pungent
0.81
Videos
Safety and Handling

Safety and Handling

GHS H Statement
H228-H314-H318
Flammable solid.
Causes severe skin burns and eye damage.
Causes serious eye damage.

P210-P240-P241-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

H228-H314-H335

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missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier
  • tert-Butyldimethylchlorosilane

Signal Word
  • Danger

Hazard Category
  • LONG-TERM AQUATIC HAZARD Chronic 2
  • Serious eye damage/eye irritation Category 1
  • Flammable solid Category 2
  • Skin corrosion/irritation Category 1 A

Hazard Statement
  • H228-Flammable solid.
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • H411-Toxic to aquatic life with long lasting effects.

Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.

Supplemental information
  • MIXTURE LIST-Contains : Chloro(1,1-dimethylethyl)dimethyl-silane

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only