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tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals
33.57 € - 381.90 €
Chemical Identifiers
CAS | 18162-48-6 |
---|---|
Molecular Formula | C6H15ClSi |
Molecular Weight (g/mol) | 150.721 |
MDL Number | MFCD00000501 |
InChI Key | BCNZYOJHNLTNEZ-UHFFFAOYSA-N |
Synonym | tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride |
PubChem CID | 28928 |
ChEBI | CHEBI:85071 |
IUPAC Name | tert-butyl-chloro-dimethylsilane |
SMILES | CC(C)(C)[Si](C)(C)Cl |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
11474364
|
Thermo Scientific Alfa Aesar
A13064.06 |
5 g |
33.57 €
5g |
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11484364
|
Thermo Scientific Alfa Aesar
A13064.14 |
25 g |
142.71 €
25g |
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11494364
|
Thermo Scientific Alfa Aesar
A13064.22 |
100 g |
381.90 €
100g |
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Description
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applicationstert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.
Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
Chemical Identifiers
18162-48-6 | |
150.721 | |
BCNZYOJHNLTNEZ-UHFFFAOYSA-N | |
28928 | |
tert-butyl-chloro-dimethylsilane |
C6H15ClSi | |
MFCD00000501 | |
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride | |
CHEBI:85071 | |
CC(C)(C)[Si](C)(C)Cl |
Specifications
124°C to 126°C | |
18162-48-6 | |
(CH3)3CSi(CH3)2Cl | |
UN2925 | |
22°C (72°F) | |
Soluble in chloroform and ethyl acetate. Insoluble in water. | |
CC(C)(C)[Si](C)(C)Cl | |
150.721 | |
CHEBI:85071 | |
97% | |
Moisture sensitive | |
tert-Butyldimethylchlorosilane |
86°C to 89°C | |
C6H15ClSi | |
MFCD00000501 | |
505999 | |
tert-butyldimethylsilyl chloride, tert-butyldimethylchlorosilane, t-butyldimethylchlorosilane, tert-butylchlorodimethylsilane, tbdms chloride, tert-butyl chloro dimethylsilane, chloro-tert-butyldimethylsilane, silane, chloro 1,1-dimethylethyl dimethyl, tbscl, t-butyldimethylsilyl chloride | |
BCNZYOJHNLTNEZ-UHFFFAOYSA-N | |
tert-butyl-chloro-dimethylsilane | |
28928 | |
150.73 | |
Pungent | |
0.81 |
Safety and Handling
GHS H Statement
H228-H314-H318
Flammable solid.
Causes severe skin burns and eye damage.
Causes serious eye damage.
P210-P240-P241-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
H228-H314-H335
missing translation for 'dotInformation' : Hazard Class: 8; Packaging Group: I
missing translation for 'einecsNumber' : 242-042-4
missing translation for 'rtecsNumber' : VV2000000
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures
- tert-Butyldimethylchlorosilane
Signal Word
- Danger
Hazard Category
- LONG-TERM AQUATIC HAZARD Chronic 2
- Serious eye damage/eye irritation Category 1
- Flammable solid Category 2
- Skin corrosion/irritation Category 1 A
Hazard Statement
- H228-Flammable solid.
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H411-Toxic to aquatic life with long lasting effects.
Precautionary Statement
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
Supplemental information
- MIXTURE LIST-Contains : Chloro(1,1-dimethylethyl)dimethyl-silane
RUO – Research Use Only