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  6. Thermo Scientific Chemicals Sulfanilamide 98%

Thermo Scientific Chemicals Sulfanilamide 98%

Product Code. 10091350
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Quantity:
100 g
500 g
2.5 kg

Description

Sulfanilamide, CAS # 63-74-1, is an organic sulfur compound that shows antibacterial activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Sulfanilamide is an organic sulfur compound with antibacterial properties that are structurally similar to the p-aminobenzoic acid (PABA)
  • It also has a competitive inhibitory capacity against dihydropteroate synthetases blocking the synthesis of folic acid
  • Sulfanilamide competes with PABA for the bacterial enzyme dihydropteroate synthase preventing, the incorporation of PABA into dihydrofolic acid, an immediate precursor of folic acid. This culminates in the inhibition of the bacterial folic acid synthesis and also the de novo synthesis of purines and pyrimidines, resulting in cell growth arrest and cell death.

Applications

  • This compound shows antibacterial activity against different species, including gram-positive, gram-negative, and Chlamydia
  • In chemical reactions, this compound can act as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution
  • Sulfanilamide shows inhibitory activity against the enzyme, carbonic anhydrase.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 63-74-1
Molecular Formula C6H8N2O2S
Molecular Weight (g/mol) 172.202
MDL Number MFCD00007939
InChI Key FDDDEECHVMSUSB-UHFFFAOYSA-N
Synonym 4-Aminobenzenesulfonamide
PubChem CID 5333
ChEBI CHEBI:45373
IUPAC Name 4-aminobenzenesulfonamide
SMILES C1=CC(=CC=C1N)S(=O)(=O)N

Specifications

Type Sulfanilamide
Physical Form Crystalline Powder
Melting Point 163.0°C to 167.0°C
Infrared Spectrum Authentic
Assay Percent Range 98%
Loss on Drying 0.5% max. (1 g, 105°C)
Linear Formula 4-(H2N)C6H4SO2NH2
Beilstein 14, 698
Merck Index 15, 9057
Packaging Plastic Bottle
Solubility Information Solubility in water: 7.5g/L (20°C).
Formula Weight 172.2
Percent Purity 98%
Color White
Quantity 500 g
Chemical Name or Material Sulfanilamide, 98%
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Safety and Handling

compliance-icons
Product Identifier
  • Sulfanilamide
 Signal Word
  • Warning
 Hazard Category
  • Skin corrosion/irritation Category 2
  • Serious eye damage/eye irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.

RUO – Research Use Only

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