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RAB5A Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 € - 410.00 €

Specifications

Antigen RAB5A
Concentration 0.22 mg/mL
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16879744
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Proteintech
20228-1-AP-20UL
20 μL
145.00 €
20µL
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16869744
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Proteintech
20228-1-AP-150UL
150 μL
410.00 €
150µL
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Description

Description

The antibody is specific to RAB5A. It has no cross reaction to RAB5B or RAB5C.

RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.
Specifications

Specifications

RAB5A
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Immunocytochemistry
Unconjugated
Rabbit
Mouse, Human
P20339, Q9CQD1
271457, 5868
Peptide
Primary
-20°C
RAB5A
0.22 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
RAB5, RAB5A, Ras related protein Rab 5A
Rab5a
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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