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Description
Islet-activating protein Pertussis toxin consists of an A protomer subunit (S1) which possesses both NAD+ glycohydrolase and ADP-ribosyltransferase activities, and B oligomer subunits (S2, S3, S4, and S5) which are responsible for attachment of the native toxin to eukaryotic cell surfaces. Pertussis toxin uncouples G proteins from receptors by ADP ribosylating a cysteine residue near the carboxyl terminus of the α subunit.
Specifications
| 2665068 | |
| 50 μg | |
| Protein | |
| Wet Ice | |
| Lyophilized |
| PAGE | |
| Store in refrigerator (2–8°C). | |
| GTPase Inhibitor | |
| G Proteins | |
| >95% |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Pertussis Toxin
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 1
- Acute toxicity Category 2
Hazard Statement
- H300-Fatal if swallowed.
- H310-Fatal in contact with skin.
- H330-Fatal if inhaled.
Precautionary Statement
- P262-Do not get in eyes, on skin, or on clothing.
- P264-Wash hands thoroughly after handling.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P310-Immediately call a POISON CENTER/doctor/.
- P330-Rinse mouth.
Supplemental information
- MIXTURE LIST-Contains : Pertussis toxin
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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