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P5CS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 17719-1-AP-20UL
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Description
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.Specifications
| P5CS | |
| Polyclonal | |
| Unconjugated | |
| ALDH18A1 | |
| ALDH18A1, GK, GPR, GSAS, P5CS, PYCS | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 361755, 56454, 5832 | |
| -20°C | |
| Liquid |
| Western Blot, Immunoprecipitation | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P54886, Q9Z110 | |
| Aldh18a1 | |
| P5CS Fusion Protein Ag12100 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG |
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