NF-L Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Description

This antibody is specific to NEFL. It has a very weak reaction to NEFM.

Involved in the maintece of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predomitly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-L is the light or low molecular weight microfilament subunit and runs on SDS-PAGE gels at approximately 70 kDa. Neurofilament are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predomitly of three major proteins called NF-L, NF-M and NF-H. NF-H is the heavy or high molecular weight microfilament subunit and runs on SDS-PAGE gels in the range 180-220kDa, with some variation in different species.