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Invitrogen™ Human Dectin-1 ELISA Kit
Human Dectin-1 Kit quantitates human Dectin-1 Kit in serum, plasma, supernatant.
Brand: Invitrogen™ EH150RB
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Description
Human Dectin-1 Kit quantitates human Dectin-1 Kit in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Dectin-1 Kit.
CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.
Specifications
| beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082 | |
| 0.082 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| Clec7a | |
| <10% | |
| HRP | |
| Research Use Only | |
| 2°C to 8°C | |
| 1 hr 20 min |
| 20 to 0.082 ng/mL | |
| Biotin | |
| Plasma, Serum, Supernatant | |
| Q9BXN2 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 96 Tests | |
| Plasma, 50 μL; Serum, 50 μL; Supernatant, 50 μL | |
| Dectin 1 (Clec7a) | |
| 4 hr 45 min |
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