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Cytiva HiTrap™ MabSelect™ SuRe Prepacked Columns
Use these columns in small-scale MAb purification in a continuous bioprocess. Cytiva Life Sciences™ HiTrap™ MabSelect™ SuRe (Superior Resistance) Prepacked Columns for fast purification of monoclonal antibodies (Mabs) from large sample volumes
364.00 € - 5604.00 €
Specifications
| Binding Capacity | ≈35mg Human lgG/mL at 2.4 min. residence time |
|---|---|
| Description | HiTrap MabSelect SuRe columns are prepacked with MabSelect SuRe, a BioProcess resin for purification of monoclonal antibodies from large sample volumes. The novel alkali-tolerant recombinant Protein A ligand allow cleaning-in-place (CIP). |
| Content And Storage | 4°C to 30°C, 20% Ethanol |
| For Use With (Application) | Chromatography System, Manual |
| Type | Pre-packed Column |
| Product Code | Brand | Type | Bed Volume | Flow Rate | Price | Quantity & Availability | |||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Type | Bed Volume | Flow Rate | Price | Quantity & Availability | |||
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11574865
|
Cytiva
11-0034-95 |
Pre-packed Column | 5 mL | <20 mL/min. |
5604.00 €
Pack of 5 |
In Stock
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|
10064394
|
Cytiva
11-0034-93 |
Pre-packed Column | 1 mL | <4 mL/min. |
1428.00 €
Pack of 5 |
In Stock
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|||
|
11758408
|
Cytiva
11-0034-94 |
Pre-packed Column | 5 mL | <20 mL/min. |
1338.00 €
Each |
In Stock
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|||
|
15137956
|
Cytiva
29049104 |
Pre-packed Column | 1 mL | <4 mL/min. |
364.00 €
1mL |
In Stock
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Description
Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.
- Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
- High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
- Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
- Designed for use with a syringe, a peristaltic pump, or a chromatography system
MabSelect
- Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
- Recombinant Protein A ligand promotes specificity of binding to Fc region of IgG; permits one-step purification
- Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
- Allows binding from samples with high expression levels of the monoclonal antibody
- Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches
- Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
- Permits significant cost savings and extension of cycles in regular production
Specifications
| ≈35mg Human lgG/mL at 2.4 min. residence time | |
| 4°C to 30°C, 20% Ethanol | |
| Pre-packed Column |
| HiTrap MabSelect SuRe columns are prepacked with MabSelect SuRe, a BioProcess resin for purification of monoclonal antibodies from large sample volumes. The novel alkali-tolerant recombinant Protein A ligand allow cleaning-in-place (CIP). | |
| Chromatography System, Manual |