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Guanidine hydrochloride, 98%, Thermo Scientific Chemicals

Guanidine hydrochloride, CAS # 50-01-1, is an ionic buffer component used for nucleic acids (DNA and RNA) and protein isolation.

31.16 € - 285.42 €

Chemical Identifiers

CAS 50-01-1
Molecular Formula CH6ClN3
Molecular Weight (g/mol) 95.53
MDL Number MFCD00013026
InChI Key PJJJBBJSCAKJQF-UHFFFAOYSA-N
Synonym guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
PubChem CID 5742
ChEBI CHEBI:32735
IUPAC Name guanidine;hydrochloride
SMILES C(=N)(N)N.Cl
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Product Code Brand Quantity Price Quantity & Availability  
11420024
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Thermo Scientific Alfa Aesar
A13543.30
250 g
31.16 €
250g
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11410024
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Thermo Scientific Alfa Aesar
A13543.0B
1000 g
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Thermo Scientific Alfa Aesar
A13543.0I
5000 g
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Description

Description

Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized in the synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Guanidine hydrochloride is the hydrochloride salt of guanidine, an acetylcholine releasing agent
  • It is a normal product of protein metabolism and is sometimes used for pyrimidine synthesis

Application

  • Guanidine hydrochloride is a powerful denaturant, useful for taking nucleic acids (DNA and RNA) and proteins out of their native conformation
  • Guanidine hydrochloride acts as a strong organic base at physiological pH
  • It is suitable for use in protein and nucleic acid purification protocols
Specifications

Chemical Identifiers

50-01-1
95.53
PJJJBBJSCAKJQF-UHFFFAOYSA-N
5742
guanidine;hydrochloride
CH6ClN3
MFCD00013026
guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
CHEBI:32735
C(=N)(N)N.Cl

Specifications

50-01-1
1.344
MFCD00013026
Hygroscopic
guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
PJJJBBJSCAKJQF-UHFFFAOYSA-N
guanidine;hydrochloride
5742
95.53
Guanidine hydrochloride
178°C to 185°C
CH6ClN3
3591990
144562
Soluble in water and ethanol.
C(=N)(N)N.Cl
95.53
CHEBI:32735
98%
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Safety and Handling

Safety and Handling

Causes serious eye irritation, May form combustible dust concentrations in air, Causes skin irritation, Harmful if swallowed or if inhaled

Serious eye damage/eye irritation (category 2), Skin corrosion/irritation (category 2), Acute toxicity (category 4)

missing translation for 'einecsNumber' : 200-002-3

missing translation for 'rtecsNumber' : MF4300000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier
  • Guanidine hydrochloride

Signal Word
  • Warning

Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2

Hazard Statement
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H332-Harmful if inhaled.

Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information
  • MIXTURE LIST-Contains : Guanidine hydrochloride

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only