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Thermo Scientific Chemicals (-)-Erythromycin, Eur.Ph.

Erythromycin (E-Mycin or erythrocin), CAS # 114-07-8, is a broad-spectrum antibiotic.

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Chemical Identifiers

CAS 114-07-8
Molecular Formula C37H67NO13
Molecular Weight (g/mol) 733.94
MDL Number MFCD00084654
InChI Key ULGZDMOVFRHVEP-RWJQBGPGSA-N
PubChem CID 12560
ChEBI CHEBI:42355
IUPAC Name (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
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Thermo Scientific Chemicals
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343880250 		25 g Glass Bottle
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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• Erythromycin is a macrolide antibiotic that works by binding the 50S ribosomal subunit and inhibiting polypeptide formation
• Erythromycin was isolated from Saccharopolyspora erythraea
Applications
• Erythromycin can be used to disrupt the growth of gram-positive and gram-negative bacteria
• Erythromycin has been shown to have motor effects in the gastrointestinal system and can be used for laboratory research on migrating motor complex activity
Specifications

Chemical Identifiers

114-07-8
733.94
ULGZDMOVFRHVEP-RWJQBGPGSA-N
CHEBI:42355
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
C37H67NO13
MFCD00084654
12560
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione

Specifications

(-)-Erythromycin
114-07-8
Authentic (Identification A)
MFCD00084654
ULGZDMOVFRHVEP-RWJQBGPGSA-N
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
12560
733.94
93.0 to 102.0% (sum of erythromycin A, B and C, on anhydrous substance); 5.0% max. erythromycin B and erythromycin C)
Colorless or White or Yellow
Powder or Crystals
138.0°C to 140.0°C
C37H67NO13
Solubility in water: +/- 2 mg/mg. Other solubilities: freely soluble in alcohols, acetone, chloroform,, acetonitrile, ethyl acetate, moderately soluble in ether, ethylenedichloride, and amyl acetate
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
733.94
CHEBI:42355
− 74.50 (20.00°C c=2,ethanol)
6.5% max. (K.F.)
(-)-Erythromycin
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Product Identifier
  • (-)-Erythromycin

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