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DR4 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 24063-1-AP-20UL
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Description
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).Specifications
| DR4 | |
| Polyclonal | |
| Unconjugated | |
| TNFRSF10A | |
| APO2, CD261, Death receptor 4, DR4, TNFRSF10A, TRAIL R1, TRAIL receptor 1, TRAILR 1, TRAILR1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 8797 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O00220 | |
| TNFRSF10A | |
| DR4 Fusion Protein Ag20927 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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