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  7. Digitonin, MP Biomedicals™

Digitonin, MP Biomedicals™

Product Code. 11461531
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Quantity:
500 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Used to solubilize receptors and permeabilize cellular and nuclear membranes. Digitonin, MP Biomedicals is a mild nonionic detergent that permeabilizes plasma membranes of eukaryotic cells by complexing with membrane cholesterol and other unconjugated &be

Digitonin has following uses:

  • Cholesterol determination
  • Use of digitonin-permeabilized adipocytes for cAMP studies
  • Solubilization of membrane proteins
  • The water soluble form can be used for the isolation of mitotic chromosomes
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 11024-24-1
Molecular Formula C56H92O29
Molecular Weight (g/mol) 1229.32
MDL Number MFCD00077729
InChI Key UVYVLBIGDKGWPX-QYLWGQLPSA-N
Synonym digitonin
PubChem CID 102004607
IUPAC Name (2S,3R,4S,5S,6R)-2-{[(2S,3R,4S,5S,6R)-2-{[(2S,3R,4S,5R,6R)-2-{[(2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(1'R,2R,2'S,3'S,4'R,7'S,8'R,9'S,12'S,13'S,15'R,16'R,18'S)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸]icosane]-3',15'-dioloxy]oxan-3-yl]oxy}-5-hydroxy-6-(hydroxymethyl)-4-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}oxan-3-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES C[C@H]1[C@H]2[C@@H](O[C@]11CCC(C)CO1)[C@@H](O)[C@H]1[C@@H]3CC[C@H]4C[C@@H](O[C@@H]5O[C@H](CO)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O[C@@H]7OC[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@H]6O[C@H](CO)[C@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)C[C@]4(C)[C@H]3CC[C@]21C

Specifications

Physical Form White Powder
Melting Point 230°C to 240°C (decomposition)(literature)
Quantity 500 mg
Specific Rotation [α]20/D −54°, c = 2.8 in methanol (Lit.)
Solubility Information Soluble in boiling water (1g/10mL). Heat for 15 minutes at 98°C. Cool and place at 4°C for 3 hrs and filter off any precipitate. Soluble in absolute alcohol (1g/57mL) and 95% alcohol (1g).
Formula Weight 1229.3
Concentration or Composition (by Analyte or Components) CriticalMicelle Concentration (CMC) <0.5mM (20–25°C) (Lit.)

Safety and Handling

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Product Identifier
  • digitonin, water soluble
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 3
  • Specific target organ toxicity after repeated exposure Category 2
 Hazard Statement
  • H301-Toxic if swallowed.
  • H373-May cause damage to organs.
 Precautionary Statement
  • P101-If medical advice is needed, have product container or label at hand.
  • P102-Keep out of reach of children.
  • P103-Read label before use.
  • P260-Do not breathe dust/fume/gas/mist/vapours/spray.
  • P264-Wash thoroughly after handling.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P321-Specific treatment (see on this label).
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : digitonin
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