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Thermo Scientific Chemicals Chloroform, Molecular Biology Reagent
106.53 € - 173.87 €
Chemical Identifiers
CAS | 67-66-3 |
---|---|
Molecular Formula | CHCl3 |
Molecular Weight (g/mol) | 119.37 |
MDL Number | MFCD00000826 |
InChI Key | HEDRZPFGACZZDS-UHFFFAOYSA-N |
Synonym | trichloromethane, formyl trichloride, methane, trichloro, trichloroform, methane trichloride, methenyl trichloride, methyl trichloride, trichlormethan, chloroforme, cloroformio |
PubChem CID | 6212 |
ChEBI | CHEBI:35255 |
SMILES | ClC(Cl)Cl |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15498679
|
Thermo Scientific Chemicals
J67241.AP |
500 mL |
106.53 €
500mL |
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15408689
|
Thermo Scientific Chemicals
J67241.K2 |
1 L |
173.87 €
1 L |
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Description
Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsChloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.
Solubility
Soluble in water at 20°C 8 g/L.
Notes
Stabilized with approx. 50 ppm amylene
Chemical Identifiers
67-66-3 | |
119.37 | |
HEDRZPFGACZZDS-UHFFFAOYSA-N | |
6212 | |
ClC(Cl)Cl |
CHCl3 | |
MFCD00000826 | |
trichloromethane, formyl trichloride, methane, trichloro, trichloroform, methane trichloride, methenyl trichloride, methyl trichloride, trichlormethan, chloroforme, cloroformio | |
CHEBI:35255 |
Specifications
-63°C | |
Colorless | |
61°C | |
Liquid | |
CHCl3 | |
UN1888 | |
14,2141 | |
Soluble in water at 20°C 8g/L. | |
ClC(Cl)Cl | |
119.37 | |
CHEBI:35255 | |
Chloroform, Molecular Biology Reagent |
67-66-3 | |
1.492 g/mL | |
Characteristic | |
1.446 | |
MFCD00000826 | |
1731042 | |
trichloromethane, formyl trichloride, methane, trichloro, trichloroform, methane trichloride, methenyl trichloride, methyl trichloride, trichlormethan, chloroforme, cloroformio | |
HEDRZPFGACZZDS-UHFFFAOYSA-N | |
chloroform | |
6212 | |
119.38 |
Safety and Handling
GHS H Statement
H351-H373-H302-H315
Suspected of causing cancer.
May cause damage to organs through prolonged or repeated exposure.
Harmful if swallowed.
Causes skin irritation.
P201-P202-P260-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
H302-H315-H319-H331-H335-H336-H351-H361d-H373
missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packaging Group: III; Proper Shipping Name: CHLOROFORM
missing translation for 'einecsNumber' : 200-663-8
missing translation for 'rtecsNumber' : FS9100000
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures
- Chloroform, Molecular Biology Reagent
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 3
- Acute toxicity Category 4
- Carcinogenicity Category 2
- Serious eye damage/eye irritation Category 2
- Reproductive toxicity Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 1
- Specific target organ toxicity Category 3
Hazard Statement
- H302-Harmful if swallowed.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H331-Toxic if inhaled.
- H336-May cause drowsiness or dizziness.
- H351-Suspected of causing cancer.
- H361d-Suspected of damaging the unborn child.
- H372-Causes damage to organs.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P311-Call a POISON CENTER/doctor/ .
Supplemental information
- MIXTURE LIST-Contains : chloroform, 1-pentane
RUO – Research Use Only
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