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CD134 Rat anti-Mouse, CoraLite 488, Clone: OX-86, Proteintech
Rat Monoclonal Antibody
Brand: Proteintech CL488-65136-100TESTS
This item is not returnable.
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Description
CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222).
Specifications
| CD134 | |
| Monoclonal | |
| 5 μL/Test | |
| Rat | |
| Primary | |
| Human, Mouse, Rat | |
| IgG1 κ |
| Flow Cytometry | |
| OX-86 | |
| CoraLite 488 | |
| 100 Tests | |
| 22163 | |
| Liquid |