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Beta Catenin Rabbit anti-Human, CoraLite 555, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech CL555-51067-100UL
This item is not returnable.
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Description
β-Catenin, also known as CTNNB1, is an evolutionarily conserved, multifunctional intracellular protein. β-Catenin is a 92-kDa protein, originally identified in cell adherens junctions (AJs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the AJs, β-catenin is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. The Wnt/β-catenin pathway is also involved in the activation of other intracellular messengers such as calcium fluxes, JNK, and SRC kinases. Deregulation of β-catenin activity is associated with multiple diseases including cancers. (PMID: 22617422; 18334222)
Specifications
| Beta Catenin | |
| Polyclonal | |
| CoraLite 555 | |
| 100 μL | |
| 1499 | |
| Liquid |
| Immunofluorescence | |
| 1000 μg/mL | |
| Rabbit | |
| Primary | |
| Human | |
| IgG |