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TCR V beta F1 Monoclonal Antibody (8A3), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen TCR1151
This item is not returnable.
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Description
TCR1151 targets TCR Beta F1 in FACS, FISH, IHC, IHC(P), IP, and WB applications and shows reactivity with Human samples. The TCR1151 immunogen is human TCR β chain constant region. TCR1151 detects TCR Beta F1 which has a predicted molecular weight of approximately 13 kDa.
The T Cell Receptor alpha beta (TCRab) is a heterodimeric membrane receptor that consists of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 proteins. TCRab participates in the activation of T-cells in response to an antigen presented in the context of MHC. Engagement of the TCRab initiates signaling cascades that μgtimately result in cellular proliferation, differentiation, cytokine production, and/or activation-induced cell death. These signaling cascades regulate T-cell development, homeostasis, activation, acquisition of effector functions and apoptosis. Cells expressing TCRab constitute the vast majority of T cells in both human and mouse.
Specifications
| TCR V beta F1 | |
| Monoclonal | |
| 0.15 mg/mL | |
| PBS with 0.5% BSA and 0.1% sodium azide | |
| 0 | |
| TRB | |
| Human TCR ß chain constant region | |
| 200 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 8A3 | |
| Unconjugated | |
| TRB | |
| T cell receptor beta locus; tcr beta f1; TCRB; TRB; TRB@ | |
| Mouse | |
| Protein G | |
| RUO | |
| 6957 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Pierce Purified Antibody(ies)
Signal Word
- Warning
Hazard Category
- Acute toxicity Category 4
Hazard Statement
- H302-Harmful if swallowed.
Precautionary Statement
- P264-Wash hands thoroughly after handling.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : sodium azide
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