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IL-4 Monoclonal Antibody (BVD4-1D11), Invitrogen™
Rat Monoclonal Antibody
Brand: Invitrogen AMC0044
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Description
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Specifications
| IL-4 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.1% sodium azide | |
| P07750 | |
| Il4 | |
| Recombinant mouse IL-4. | |
| 500 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2b |
| ELISA, Flow Cytometry, Neutralization | |
| BVD4-1D11 | |
| Unconjugated | |
| Il4 | |
| B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra | |
| Rat | |
| purified | |
| RUO | |
| 16189 | |
| -20°C | |
| Liquid |
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