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Transferrin Receptor Monoclonal Antibody (R17217.1.4), FITC, Invitrogen™
Rat Monoclonal Antibody
Brand: Invitrogen MA517922
This item is not returnable.
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Description
MA5-17922 targets CD71/transferrin receptor in FACS applications and shows reactivity with Mouse samples.
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
Specifications
| Transferrin Receptor | |
| Monoclonal | |
| 0.1 mg/mL | |
| PBS with 4-5mg/mL BSA and 0.02% sodium azide | |
| Q62351 | |
| TFRC | |
| Friend erythroleukemia 745.6 induced for 5 days in 1.5% dimethyl sulfoxide. | |
| 300 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Flow Cytometry | |
| R17217.1.4 | |
| FITC | |
| TFRC | |
| 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr | |
| Rat | |
| Protein G | |
| RUO | |
| 22042 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. | |
| Liquid |