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AKT Pan Monoclonal Antibody (J.314.4), Invitrogen™
Rabbit Monoclonal Antibody
Brand: Invitrogen MA514916
This item is not returnable.
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Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other related proteins.
AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
Specifications
| AKT Pan | |
| Monoclonal | |
| 35 μg/mL | |
| 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5 | |
| P31749, P31750, P31751, P47196, P47197, Q60823, Q63484, Q8INB9, Q9WUA6, Q9Y243 | |
| AKT1, Akt2, Akt3 | |
| Synthetic peptide corresponding to residues in the carboxy-terminal sequence of mouse Akt | |
| 100 μL | |
| Primary | |
| Drosophila, Human, Mouse, Non-human Primate, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| J.314.4 | |
| Unconjugated | |
| Akt2 | |
| 2410016A19Rik; AI851531; akt; Akt kinase; AKT serine/threonine kinase 1; AKT serine/threonine kinase 2; AKT serine/threonine kinase 3; Akt/PKB; Akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; Akt2; AKT2 kinase; AKT3; AKT3 kinase; akt3a; AW554154; bovine protein kinase B; cb945; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; D930002M15Rik; DAKT; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; DKFZp434N0250; Dmel\CG4006; Dmel_CG4006; DPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; HIHGHH; kinase Akt1; l(3)04226; l(3)89Bq; MGC99656; MPPH; MPPH2; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 1; murine thymoma viral (v-akt) oncogene homolog 2; Nmf350; pAkt; P-AKT; pan akt; PKB; PKB alpha; PKB beta; PKB gamma; PKB/Akt; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBB; PKBbeta; Pkbg; PKBgamma; PKB-GAMMA; PRKBA; PRKBB; PRKBG; Protein kinase Akt-2; protein kinase Akt-3; Protein kinase B; protein kinase B alph | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 10000, 11651, 11652, 207, 208, 23797, 24185, 25233, 29414, 41957 | |
| -20°C | |
| Liquid |