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  8. 5-(Trifluoromethoxy)isatin, 98%, Thermo Scientific Chemicals

5-(Trifluoromethoxy)isatin, 98%, Thermo Scientific Chemicals

Product Code. 11467176
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Quantity:
1 g
5 g
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This item is not returnable. View return policy

Description

5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-(Trifluoromethoxy)isatin is used as a reactant for preparation of oxindole derivatives as TAk1 kinase inhibitors and of isatin thiosemicarbazones via condensation with thiosemicarbazones as herpes simplex virus (HSV) inhibitors. It is also used as a reactant for synthesis of 3-substituted 2-indolinone RET kinase inhibitors and for preparation of indolone acetamides as antiseizure agents.

Solubility
Insoluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 169037-23-4
Molecular Formula C9H4F3NO3
Molecular Weight (g/mol) 231.13
MDL Number MFCD00192524
InChI Key XHAJMVPMNOBILF-UHFFFAOYSA-N
Synonym 5-trifluoromethoxy isatin, 5-trifluoromethoxy indoline-2,3-dione, 5-trifluoromethoxy-1h-indole-2,3-dione, 5-trifluoromethoxyisatin, 1h-indole-2,3-dione, 5-trifluoromethoxy, 5-trifluoromethoxy-2,3-indolinedione, buttpark 34\07-90, acmc-209dz9, d0zr2t
PubChem CID 2732752
IUPAC Name 5-(trifluoromethoxy)-1H-indole-2,3-dione
SMILES C1=CC2=C(C=C1OC(F)(F)F)C(=O)C(=O)N2

Specifications

Melting Point 170°C to 172°C
Quantity 5 g
Solubility Information Insoluble in water.
Formula Weight 231.13
Percent Purity 98%
Chemical Name or Material 5-(Trifluoromethoxy)isatin

RUO – Research Use Only

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