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  8. 2,2-Difluoroacetophenone, 95%, Thermo Scientific Chemicals

2,2-Difluoroacetophenone, 95%, Thermo Scientific Chemicals

Product Code. 11379959
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Quantity:
250 mg
1 g
5 g
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This item is not returnable. View return policy

Description

2,2-Difluoroacetophenone acts as an intermediate in the preparation of various substances such as pharmaceuticals. Further, it is used in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides. In addition to this, it undergoes reduction with (-)-diisopinocampheylchloroborane chloride to get R-alcohols of purity 85% ee.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,2-Difluoroacetophenone acts as an intermediate in the preparation of various substances such as pharmaceuticals. Further, it is used in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides. In addition to this, it undergoes reduction with (-)-diisopinocampheylchloroborane chloride to get R-alcohols of purity 85% ee.

Solubility
Immiscible with water.

Notes
Incompatible with strong oxidizing agents and strong acids.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 395-01-7
Molecular Formula C8H6F2O
Molecular Weight (g/mol) 156.132
MDL Number MFCD06246879
InChI Key OLYKCPDTXVZOQF-UHFFFAOYSA-N
Synonym 2,2-difluoroacetophenone, alpha,alpha-difluoroacetophenone, 2,2-difluoro-1-phenyl-ethanone, 2,2-difluoro-1-phenylethan-1-one, a,a-difluoroacetophenone, ethanone, 2,2-difluoro-1-phenyl, difluoromethyl phenyl ketone, difluoroacetophenone, acmc-20aojw, acetophenone, 2,2-difluoro
PubChem CID 273286
IUPAC Name 2,2-difluoro-1-phenylethanone
SMILES C1=CC=C(C=C1)C(=O)C(F)F

Specifications

Melting Point 48°C to 50°C
Boiling Point 53°C to 54°C (12 mmHg)
Odor Characteristic
Refractive Index 1.4955
Quantity 5 g
Solubility Information Immiscible with water.
Formula Weight 156.13
Percent Purity 95%
Chemical Name or Material 2,2-Difluoroacetophenone

RUO – Research Use Only

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